You’ve probably said it. And I’m also guilty of saying, “My pancreas is dead”. But is it true?
Even though type 1 diabetics essentially cannot produce enough insulin to live, it doesn’t mean that the organ that produces it, the pancreas, is dead.
The pancreas has many functions other than the beta cells that produce insulin. The pancreas has many important roles for the endocrine system (regulates blood sugar) and the exocrine system (helps digestion).
Apart from still secreting enzymes to break down food, your pancreas probably still produces trace amounts of insulin.
A C-peptide test will measure how well your body produces insulin. When your pancreas produces insulin, via beta cells, the process also releases C-Peptide. So measuring the amount of C-Peptide in your body will indicate how effective your pancreas is at producing insulin.
One of the most compelling researchers who disproves the theory that the pancreas is dead, is Dr. Denise L. Faustman. As found in this article on page 2:
To our astonishment, when all weekly blood sera were analysed by an ultrasensitive C peptide assay at the end of the double-blind trial, all long-term type 1 diabetic participants— recipients of immunotherapy as well as placebo volunteers, even before randomisation—had low yet detectable levels of insulin secretion as measured by C peptide. We were galvanised to conduct a follow-up study of nearly 200 long-term diabetic patients in which we assayed C-peptide using the same ultrasensitive assay, which has a lower detection limit of 1.5–2.5 pmol/l. In this study, C-peptide secretion decayed gradually over the course of 20 years, not the 1–2 year honeymoon time course . Also, patients with hyperglycaemia had higher C-peptide levels than those with normoglycaemia, a finding that indicated appropriate islet beta cell function.
When explaining what type 1 diabetes is, it’s easiest to say that the pancreas is dead, but it’s important to spread FACTS to raise awareness. The pancreas has MANY functions, and unfortunately, it cannot fulfill one of the very important ones.
Anyway, your pancreas is NOT dead.
P.S. Dr. Faustman has incredibly compelling research and trials to cure type 1 diabetes.